Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides

Zhichao Xiong; Hongqiang Qin; Hao Wan; Guang Huang; Zhang Zhang; Jing Dong; Lingyi Zhang; Weibing Zhang; Hanfa Zou

doi:10.1039/c3cc45008b

Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides

Chem Commun (Camb). 2013 Oct 18;49(81):9284-6. doi: 10.1039/c3cc45008b.

Authors

Zhichao Xiong¹, Hongqiang Qin, Hao Wan, Guang Huang, Zhang Zhang, Jing Dong, Lingyi Zhang, Weibing Zhang, Hanfa Zou

Affiliation

¹ Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Shanghai 200237, China. weibingzhang@ecust.edu.cn.

PMID: 23995097
DOI: 10.1039/c3cc45008b

Abstract

Magnetic nanoparticles (MNPs) coated with multilayer polysaccharide shells have been fabricated using a layer-by-layer approach via the alternate deposition of hyaluronan (HA) and chitosan (CS) onto the surface, and the hydrophilic materials were utilized for effective and selective enrichment of glycopeptides in biological samples.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chitosan / chemistry*
Glycopeptides / analysis*
Humans
Hyaluronic Acid / chemistry*
Immunoglobulin G / metabolism
Magnetite Nanoparticles / chemistry*
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization*

Substances

Glycopeptides
Immunoglobulin G
Magnetite Nanoparticles
Hyaluronic Acid
Chitosan