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Vaccine. 2013 Nov 19;31(48):5627-33. doi: 10.1016/j.vaccine.2013.08.045. Epub 2013 Aug 28.

Global distribution of group A rotavirus strains in horses: a systematic review.

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  • 1Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Hungária krt. 21, Budapest 1143, Hungary. Electronic address: suesy86@gmail.com.

Abstract

Group A rotavirus (RVA) is a major cause of diarrhea and diarrhea-related mortality in foals in parts of the world. In addition to careful horse farm management, vaccination is the only known alternative to reduce the RVA associated disease burden on horse farms. The precise evaluation of vaccine effectiveness against circulating strains needs enhanced surveillance of equine RVAs in areas where vaccine is already available or vaccine introduction is anticipated. Therefore, we undertook the overview of relevant information on epidemiology of equine RVA strains through systematic search of public literature databases. Our findings indicated that over 99% of equine RVA strains characterized during the past three decades belonged to two common genotypes, G3P[12] and G14P[12], whereas most of the minority equine RVA strains were probably introduced from a heterologous host by interspecies transmission. These baseline data on RVA strains in horses shall contribute to a better understanding of the spatiotemporal dynamics of strain prevalence in vaccinated and non-vaccinated herds.

Copyright © 2013 Elsevier Ltd. All rights reserved.

KEYWORDS:

Epidemiology; Equine; Equus caballus; Rotavirus; Surveillance; Vaccination

[PubMed - indexed for MEDLINE]
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