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J Thorac Dis. 2013 Aug;5(4):E170-3. doi: 10.3978/j.issn.2072-1439.2013.08.40.

A case report of pulmonary cryptococcosis presenting as endobronchial obstruction.

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  • 1Department of Infection Control, Zhongshan Hospital Fudan University, Shanghai, China.

Abstract

Cryptococcosis presenting as endobronchial obstruction was scarce. We report a case of patient with cryptococcosis. A chest CT scan showed masses in the right upper lobe and right hilar, with evidence of narrowing of the right upper lobe bronchus. PET-CT scans showed the mass in the bronchus with the high mSUVs. A biopsy specimen was taken from the mass by lung puncture biopsy and showed cryptococcus infection. Culture of lung tissue was C. neoformans. The serum was positive for cryptococcal antigen, with a titer of more than 1(:)1,280. He was successfully treated using amphotericin B liposome. This case is worth discussing because it was cryptococcosis presenting as endobronchial obstruction that is often considered tumor.

KEYWORDS:

Cryptococcosis; airway obstruction; amphotericin B liposome

PMID:
23991332
[PubMed]
PMCID:
PMC3755657
Free PMC Article

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