A rhodamine-based fluorescent probe for detecting Hg(2+) in a fully aqueous environment

Xiaoli Chen; Xiangming Meng; Shuxing Wang; Yulei Cai; Yifan Wu; Yan Feng; Manzhou Zhu; Qingxiang Guo

doi:10.1039/c3dt51279g

A rhodamine-based fluorescent probe for detecting Hg(2+) in a fully aqueous environment

Dalton Trans. 2013 Oct 1;42(41):14819-25. doi: 10.1039/c3dt51279g.

Authors

Xiaoli Chen¹, Xiangming Meng, Shuxing Wang, Yulei Cai, Yifan Wu, Yan Feng, Manzhou Zhu, Qingxiang Guo

Affiliation

¹ Department of Chemistry, Anhui University, Hefei 230039, P. R. China. mengxm@ahu.edu.cn fy70@163.com.

PMID: 23986178
DOI: 10.1039/c3dt51279g

Abstract

A water-soluble fluorescent probe for Hg(2+) based on a rhodamine B derivative was designed and synthesized. The new probe showed reversible colorimetric and fluorescent response to Hg(2+) in a fully aqueous solution. The probe exhibited real-time detection of Hg(2+) with high selectivity in media containing less than 1% organic cosolvent. Furthermore, bioimaging studies indicated that the new probe was cell permeable and suitable for the real-time imaging of Hg(2+) in living cells by confocal microscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Survival
Colorimetry
Crystallography, X-Ray
Fluorescence
Fluorescent Dyes / chemical synthesis
Fluorescent Dyes / chemistry*
HeLa Cells
Humans
Hydrogen-Ion Concentration
Mercury / analysis*
Models, Molecular
Molecular Structure
Rhodamines / chemical synthesis
Rhodamines / chemistry*
Solubility
Spectrometry, Fluorescence
Spectrophotometry, Ultraviolet
Water / chemistry

Substances

Fluorescent Dyes
Rhodamines
Water
Mercury
rhodamine B