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Urology. 2014 Jan;83(1):6-11. doi: 10.1016/j.urology.2013.07.009. Epub 2013 Aug 23.

Melanoma of the glans penis and urethra.

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  • 1Department of Surgery, Zagreb Clinical Hospital Center, Zagreb, Croatia. Electronic address:
  • 2Department of Surgery and Urology, Zabok General Hospital, Zabok, Croatia.
  • 3Department of Surgery, University Clinical Center Maribor, Maribor, Slovenia.
  • 4Department of Surgery, Zagreb Clinical Hospital Center, Zagreb, Croatia.


Primary melanoma of the glans or male urethra is a rare malignant tumor with high mortality. We searched PubMed and found 129 articles reporting on 220 patients. All articles were case reports or case series. Median patient age was 65 years. Median survival was 28 months, with 5-year survival in approximately 10%. All patients who survived over 5 years had a localized disease (stage I/A) with invasion depth <3-3.5 mm. Wide local excision with sentinel lymph node biopsy is the treatment of choice for patients with localized disease. For advanced disease, the prognosis is poor.

Copyright © 2014 Elsevier Inc. All rights reserved.

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