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Acta Radiol. 2013 Aug 22;55(5):545-553. [Epub ahead of print]

Low-contrast-dose protocol in cardiac CT: 20% contrast dose reduction using 100 kVp and high-tube-current-time setting in 256-slice CT.

Author information

  • 1Diagnostic Radiology, Amakusa Medical Center, Kumamoto, Japan Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Japan masafkidoh@yahoo.co.jp.
  • 2Diagnostic Radiology, Amakusa Medical Center, Kumamoto, Japan Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Japan.
  • 3Department of Cardiology, Amakusa Medical Center, Kumamoto, Japan.
  • 4Department of Surgery, Amakusa Medical Center, Kumamoto, Japan.
  • 5Department of Neurosurgery, Amakusa Medical Center, Kumamoto, Japan.
  • 6Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Japan.

Abstract

BACKGROUND:

The use of the smallest contrast dose is highly desirable in performing cardiac computed tomography (CT), especially for patients with cardiovascular diseases to prevent contrast-induced nephropathy.

PURPOSE:

To evaluate the feasibility of 20% reduced contrast dose protocol in cardiac CT using 100 kVp and high-tube-current-time product setting.

MATERIAL AND METHODS:

Fifty patients were scanned with our conventional 120 kVp protocol, and the other 50 patients underwent scans using a tube voltage of 100 kVp, a high-tube-current-time product, and a 20% reduced contrast dose. We evaluated estimated effective dose (ED), CT attenuation, image noise, and contrast-to-noise ratio (CNR) of the ascending aorta. We also evaluated CT attenuation of the coronary arteries. Two radiologists independently assessed image quality of coronary arteries.

RESULTS:

There was no significant difference in the ED between the 100 kVp and 120 kVp protocols (21.7 mSv ± 1.6 vs. 21.8 mSv ± 1.1, P = 0.65). There was no significant difference in the CNR of the ascending aorta between the 100 kVp and 120 kVp protocols (18.8 ± 3.5 vs. 18.7 ± 3.8, P = 0.98). Mean CT attenuation of the coronary arteries of the 100 kVp protocols was significantly higher than that of 120 kVp protocols (P < 0.05). There was no significant difference in the overall image quality of the coronary artery between the 100 kVp and 120 kVp protocols (3.7 ± 0.4 vs. 3.7 ± 0.5, P = 0.65).

CONCLUSION:

For cardiac CT a voltage setting of 100 kVp and a high-tube-current-time product enable 20% reduction in the contrast dose without affecting the quality of coronary artery images compared with a 120 kVp and standard-contrast-dose CT protocol.

© The Foundation Acta Radiologica 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

KEYWORDS:

Low contrast dose; contrast-induced nephropathy; coronary CT angiography; low kilo voltage; multidetector CT

PMID:
23969265
[PubMed - as supplied by publisher]
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