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IEEE/ACM Trans Comput Biol Bioinform. 2013 Aug 16. [Epub ahead of print]

Chemical Name Extraction based on Automatic Training Data Generation and Rich Feature Set.

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  • 1IBM, San Jose.

Abstract

The automation of extracting chemical names from text has significant value to biomedical and life science research. A major barrier in this task is the difficulty of getting a sizable and good quality data to train a reliable entity extraction model. Another difficulty is the selection of informative features of chemical names, since comprehensive domain knowledge on chemistry nomenclature is required. Leveraging the random text generation techniques, we explore the idea of automatically creating training sets for the task of chemical name extraction. Assuming the availability of an incomplete list of chemical names, called a dictionary, we are able to generate well-controlled, random, yet realistic chemical-like training documents. We statistically analyze the construction of chemical names based on the incomplete dictionary, and propose a series of new features, without relying on any domain knowledge. Compared to state-of-the-art models learned from manually labeled data and domain knowledge, our solution shows better or comparable results in annotating real-world data with least human effort. Moreover, we report an interesting observation about the language for chemical names. That is, both the structural and semantic components of chemical names follow Zipfian distribution, which shows resemblance to many natural languages.

PMID:
23959634
[PubMed - as supplied by publisher]
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