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Clin Lab Med. 2013 Sep;33(3):527-52. doi: 10.1016/j.cll.2013.03.003.

Advanced techniques for detection and identification of microbial agents of gastroenteritis.

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  • 1Luminex Corporation, 12212 Technology Boulevard, Austin, TX 78727, USA.


Gastroenteritis persists as a worldwide problem, responsible for approximately 2 million deaths annually. Traditional diagnostic methods used in the clinical microbiology laboratory include a myriad of tests, such as culture, microscopy, and immunodiagnostics, which can be labor intensive and suffer from long turnaround times and, in some cases, poor and Yi-Wei Tang sensitivity. This article reviews recent advances in genomic and proteomic technologies that have been applied to the detection and identification of gastrointestinal pathogens. These methods simplify and speed up the detection of pathogenic microorganisms, and their implementation in the clinical microbiology laboratory has potential to revolutionize the diagnosis of gastroenteritis.

Copyright © 2013 Elsevier Inc. All rights reserved.


Clostridium difficile; Gastroenteritis; Multiplex polymerase chain reaction; Next-generation sequencing; Suspension array

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