Abstract
The myofibroblasts have dual characteristics of smooth muscle cells and fibroblasts. In repairing tissular wound, myofibroblasts are involved in fibrogenesis and remodeling the extracellular matrix of the fibrotic cascades reaction. The review describes the morphological characteristics and biological behaviors of myofibroblasts and the application of skin wound age determination, which may provide reference for research in forensic medicine.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Actins / metabolism
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Animals
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Cell Differentiation*
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Cells, Cultured
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Extracellular Matrix / metabolism
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Fibroblasts / cytology
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Fibroblasts / metabolism
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Fibroblasts / physiology
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Forensic Pathology / methods*
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Humans
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Muscle, Smooth / cytology
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Muscle, Smooth / physiology
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Myofibroblasts* / cytology
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Myofibroblasts* / metabolism
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Myofibroblasts* / physiology
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Skin / injuries
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Time Factors
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Wound Healing*
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Wounds and Injuries / metabolism
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Wounds and Injuries / pathology