Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Clin Chim Acta. 2013 Oct 21;425:77-9. doi: 10.1016/j.cca.2013.07.020. Epub 2013 Jul 29.

UriSed as a screening tool for presumptive diagnosis of urinary tract infection.

Author information

  • 1Division of Clinical Pathology, University of Campinas/UNICAMP, Campinas, SP, Brazil.

Abstract

BACKGROUND:

Although a quantitative urine culture is essential for the final diagnosis of urinary tract infection, it is time-consuming and an expensive procedure. Effective screening tests would be a promising alternative to provide immediate results for the clinician and eliminate unnecessary culturing for most of the negative samples. The aim of this study was to evaluate the performance of an automated sediment analyzer (UriSed) as screening tool for presumptive diagnosis of urinary tract infection.

METHODS:

We studied 1379 fresh midstream clean-catch urine samples from children to elderly. All samples were submitted to automated sediment analysis (UriSed) and quantitative urine culture (CLED medium agar).

RESULTS:

The sediment analyzer detected leukocyturia and/or significant bacteriuria with sensitivity of 97%, specificity of 59%, positive predictive value of 27%, negative predictive value of 99%, and accuracy of 64% at cutoff values of bacteria count ≥12.6 elements/hpf and WBC ≥6 cells/hpf. These data suggest a potential 52% reduction of unnecessary urine cultures.

CONCLUSION:

The UriSed seems to be an efficient tool for screening UTI with high sensitivity and low rate of false-negative results.

© 2013.

KEYWORDS:

Screening; Sediment analyzer; Urinalysis; Urinary tract infection

PMID:
23906796
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk