Inhibitory synaptic plasticity: spike timing-dependence and putative network function

Front Neural Circuits. 2013 Jul 18:7:119. doi: 10.3389/fncir.2013.00119. eCollection 2013.

Abstract

While the plasticity of excitatory synaptic connections in the brain has been widely studied, the plasticity of inhibitory connections is much less understood. Here, we present recent experimental and theoretical findings concerning the rules of spike timing-dependent inhibitory plasticity and their putative network function. This is a summary of a workshop at the COSYNE conference 2012.

Keywords: GABAergic transmission; chloride dynamics; electrophysiology; modeling and simulations; network dynamics and function; spike timing-dependent plasticity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Action Potentials / physiology*
  • Animals
  • Humans
  • Inhibitory Postsynaptic Potentials / physiology
  • Nerve Net / physiology*
  • Neural Inhibition / physiology*
  • Neuronal Plasticity / physiology*
  • Synapses / physiology*
  • Time Factors