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Parkinsonism Relat Disord. 2013 Nov;19(11):991-4. doi: 10.1016/j.parkreldis.2013.06.018. Epub 2013 Jul 21.

Sleep and impulsivity in Parkinson's disease.

Author information

  • 1Department of Neurology, Emory University School of Medicine, 1841 Clifton Road NE, Atlanta, GA 30329, USA. Electronic address: mscullin521@gmail.com.

Abstract

BACKGROUND:

Impulsive behavior and poor sleep are important non-motor features of Parkinson's disease (PD) that negatively impact the quality of life of patients and their families. Previous research suggests a higher level of sleep complaints in PD patients who demonstrate impulsive behaviors, but the nature of the sleep disturbances has yet to be comprehensively tested.

METHODS:

Consecutive idiopathic PD patients (N = 143) completed the Minnesota Impulse Disorder Interview and a sleep questionnaire that assessed sleep efficiency, excessive daytime sleepiness, restless legs symptoms, snoring, dreams/nightmares, and nocturia. Patients were also given a Unified Parkinson's Disease Rating Scale motor examination and they completed cognitive testing.

RESULTS:

Impulsive PD patients endorsed more sleep complaints than non-impulsive PD patients. The group difference was primarily attributable to poor sleep efficiency (e.g., greater nocturnal awakenings), p < .01, and greater daytime sleepiness, p < .01, in the impulsive PD patients. Interestingly, restless legs symptoms were also greater in the impulsive PD patients, p < .05. The results could not be explained by medications or disease severity.

CONCLUSIONS:

Poor sleep efficiency, restless legs symptoms, and increased daytime sleepiness are associated with impulsivity in PD. Longitudinal studies are needed to determine whether sleep disturbances precede impulsivity in PD.

Copyright © 2013 Elsevier Ltd. All rights reserved.

KEYWORDS:

Excessive daytime sleepiness; Impulse control disorder; Parkinson's disease; Restless legs syndrome; Sleep

PMID:
23880026
[PubMed - indexed for MEDLINE]
PMCID:
PMC3878049
Free PMC Article
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