Send to:

Choose Destination
See comment in PubMed Commons below
Bull Environ Contam Toxicol. 2013 Sep;91(3):324-9. doi: 10.1007/s00128-013-1061-0. Epub 2013 Jul 23.

Assessment of in vivo estrogenic response and identification of environmental estrogens in influent and effluent from a sewage treatment plant.

Author information

  • 1School of Physics and Chemistry, Henan Polytechnic University, Jiaozuo, 454003, People's Republic of China.


The in vivo estrogenic response and estrogenic contents of the influent and effluent collected from a sewage treatment plant located in Jiaozuo were assessed. The bioassay showed significant serum vitellogenin (VTG) induction in all the treated male goldfish (Carassius auratus) and significant gonad atrophies were only observed in the fish induced the most VTG expressions. Six target estrogens (estrone, 17β-estradiol, 17α-ethynylestradiol, 4-n-octylphenol, 4-n-nonylphenol and bisphenol A) were detected in different polar fractions, with the exception of the 25 % and 50 % methanol fractions extracted from the influent and the 25 %, 50 %, 95 % and 100 % methanol fractions extracted from the effluent. For both the influent and effluent, natural and synthetic steroidal estrogens were detected in those extracted fractions induced the most abundant VTG expressions.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk