Send to:

Choose Destination
See comment in PubMed Commons below
Contact Dermatitis. 2013 Aug;69(2):112-7. doi: 10.1111/cod.12041.

A simple tool with which to study the course of chronic hand eczema in clinical practice: a reduced-item score.

Author information

  • 1Department of Dermatology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.



Physicians need a simple, disease-specific tool with which to assess disease severity and the effect of therapeutic intervention in patients with chronic hand eczema. The currently available clinical scoring systems include numerous items, which makes them laborious to complete and limit their use in daily practice.


To develop a simple tool with which to assess disease severity of patients with chronic hand eczema.


We evaluated two tools, the Hand Eczema Severity Index (HECSI) and the Hand Eczema Area and Severity score, to determine their ability to predict the Investigator's Global Assessment (IGA) of disease severity in patients with moderate to severe hand eczema. We used a stepwise reduction analysis to determine a minimal set of significantly contributing items for predicting IGA.


A three-item score, based on the highest observed value of induration, fissuring, and scaling, predicted IGA with a correlation of 0.667. The HECSI predicted the IGA with a correlation of 0.675.


On the basis of this analysis, we propose a simple tool for clinical decision-making and evaluation of therapeutic intervention in daily practice.

© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.


chronic hand eczema; clinical severity; reduced item score

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Write to the Help Desk