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Cardiovasc Intervent Radiol. 2013 Dec;36(6):1704-6. doi: 10.1007/s00270-013-0692-1. Epub 2013 Jul 10.

Cholecystokinin-assisted hydrodissection of the gallbladder fossa during FDG PET/CT-guided liver ablation.

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  • 1Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, Box 77, 1275 York Avenue, New York, NY, 10065, USA,


A 68-year-old female with colorectal cancer developed a metachronous isolated fluorodeoxyglucose-avid (FDG-avid) segment 5/6 gallbladder fossa hepatic lesion and was referred for percutaneous ablation. Pre-procedure computed tomography (CT) images demonstrated a distended gallbladder abutting the segment 5/6 hepatic metastasis. In order to perform ablation with clear margins and avoid direct puncture and aspiration of the gallbladder, cholecystokinin was administered intravenously to stimulate gallbladder contraction before hydrodissection. Subsequently, the lesion was ablated successfully with sufficient margins, of greater than 1.0 cm, using microwave with ultrasound and FDG PET/CT guidance. The patient tolerated the procedure very well and was discharged home the next day.

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