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J Perinat Med. 2013 Nov;41(6):701-3. doi: 10.1515/jpm-2013-0064.

Is pathologic confirmation of placental abruption more reliable in cases due to chronic etiologies compared with acute etiologies?

Abstract

BACKGROUND:

Pathology laboratories often receive requests for confirmation of abruption; however, pathologically, abruption can only be confirmed by the presence of adherent blood clot on the maternal surface that is indenting the underlying placental parenchyma.

DESIGN:

We evaluated whether abruptions due to more chronic underlying medical conditions are more likely to have a retained indenting retroplacental clot that is detectable by the pathologist than abruptions due to acute etiologies. This was a retrospective review from January 1995 to June 2012 of cases with a clinical and/or pathologic diagnosis of abruption. Data were analyzed utilizing Fisher's exact test.

RESULTS:

Ninety-six cases had sufficient available information for analysis. There was a significant association between pathologic identification of abruption and chronic risk factors (P=0.03). Twenty-five percent of cases with acute risk factors and 60% of cases with chronic risk factors had abruption confirmed at pathologic evaluation (P=0.12).

CONCLUSION:

Pathologically confirmable abruption is associated with chronic risk factors. There was a trend towards chronic risk factors leading to greater likelihood of pathologic confirmation of abruption than acute risk factors, but it did not reach statistical significance.

PMID:
23828421
[PubMed - indexed for MEDLINE]
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