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Dermatol Clin. 2013 Jul;31(3):363-85. doi: 10.1016/j.det.2013.04.010. Epub 2013 Jun 14.

Introduction to autoinflammatory syndromes and diseases.

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  • 1Department of Medicine, Baylor University Medical Center and Texas A&M Medical School, 3500 Gaston Avenue, Dallas, TX 75246, USA. drA@dermcenter.us

Abstract

Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and genetics. These diseases often present with skin manifestations and the dermatologist may not recognize the constellation of symptoms and medical history as a systemic inflammatory disease. Dermatologists would benefit from a deeper understanding of these diseases and the new treatments available for them.

Copyright © 2013 Elsevier Inc. All rights reserved.

KEYWORDS:

Autoinflammation; Familial Mediterranean fever; Inflammasome; Interleukins; Recurrent fever

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