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Mini Rev Med Chem. 2013 Oct;13(11):1656-63.

An update on saccharide arrays.

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  • 1College of Chemistry, Chongqing Normal University, Chongqing, 401331, China.


Saccharide arrays are powerful tools to investigate the saccharide-mediated recognition events in highthroughput mode. Many methods have been used to immobilize the saccharides on support surface in the array format. The array-based technologies were widely utilized to analyze the characters of saccharide-binding lectins and antibodies, quantitatively determine saccharide-protein interactions, detect cells and pathogens, identify disease-related antisaccharide antibodies for diagnosis, and fast assess substrate specificities of glycosyltransferases. This review has mainly summarized the fabrication methods of saccharide arrays and their applications in recent years.

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