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J Spinal Cord Med. 2013 Mar;36(2):157-60. doi: 10.1179/2045772312Y.0000000048.

Spinal giant cell tumor in tuberous sclerosis: case report and review of the literature.

Author information

  • 1University of Rome Tor Vergata, Rome, Italy. mff77@libero.it

Abstract

BACKGROUND:

Patients affected by tuberous sclerosis (TS) have a greater incidence of tumors than the healthy population. Spinal tumours in TS are reported very rarely and consist mainly of sacrococcygeal and cervical chordomas.

METHOD:

Case report.

FINDINGS:

A 21-year-old man, affected by TS, presented a spinal dorsal T2 tumor that caused medullary compression. He underwent decompressive laminectomy and microsurgical excision of a giant cell tumor and an associated aneurysmal bone cyst. Postoperative hypofractionated radiotherapy was performed on the surgical field. At 2.4 years of follow-up the patient reported total recovery of neurological deficits and was free from tumor recurrence.

CONCLUSION:

Considering this association, which is the first reported in the literature, spinal magnetic resonance imaging with gadolinium should be performed at the onset of spinal pain in patients affected by TS.

PMID:
23809532
[PubMed - indexed for MEDLINE]
PMCID:
PMC3595965
Free PMC Article
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