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J Dermatol. 2013 Sep;40(9):711-4. doi: 10.1111/1346-8138.12211. Epub 2013 Jun 27.

Transdermal nicotine patches for eosinophilic pustular folliculitis.

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  • 1Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.


We previously reported the clinical effectiveness of transdermal nicotine patches for the treatment of skin disorders with eosinophilic infiltration such as Kimura's disease, erythema nodosum and eosinophilic pustular folliculitis (EPF). We assessed the efficacy and safety of transdermal nicotine patches for EPF. We treated eight patients with EPF with transdermal nicotine patches and evaluated the treatment response by performing overall lesional assessment. Excellent 77and good responses were obtained in five and one patient(s), respectively. In the other two patients, the lesions remained unchanged. No severe adverse effects were observed. Our results suggest that transdermal nicotine patches may be useful and safe in the treatment of EPF.

© 2013 Japanese Dermatological Association.


Kimura's disease; eosinophilic infiltration; eosinophilic pustular folliculitis; erythema nodosum; nicotine patches

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