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Eur J Gynaecol Oncol. 1990;11(2):141-4.

Ovarian sex cord tumor with annular tubules and Peutz-Jeghers syndrome.

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  • 1Department of Obstetrics and Gynaecology, Virgen de las Nieves Regional Hospital, Granada.


A case of ovarian sex cord tumor with annular tubules (SCTAT) is described in a patient with Peutz-Jeghers syndrome. The patient had undergone surgery at age 19 years for intestinal invagination caused by intestinal polyposis, and the subsequently had seven pregnancies. Of the four children surviving at the time of this study, all had intestinal polyposis. The ovarian tumor was discovered during a routine examination, although the patient had suffered moderate menstrual disorders and hypermenorrhea for several months previously. Eight years after surgery the patient remains free of symptoms. A review of the bibliography shows that sex cord tumors with annular tubules are very rare. Initially described by Scully in 1970, these usually benign tumors appear frequently in patients with Peutz-Jeghers syndrome. They are considered to originate from granulosa cells, and grow in patterns reminiscent of Sertoli cells.

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