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Bull Soc Pathol Exot. 2013 Aug;106(3):156-9. doi: 10.1007/s13149-013-0296-7. Epub 2013 Jun 21.

[Neurological disorders related to vitamin B12 deficiency in prisons in Guinea: a 22-case study].

[Article in French]

Author information

  • 1Service de neurologie, CHU Conakry, Conakry, République de Guinée.

Abstract

Neurological disorders related to vitamin B12 deficiency are common in prisons of tropical Africa. We collected 22 cases (20 men and 2 women). They all showed vitamin B12 deficiency associated with neurological signs that were represented by sclerosis combined with bone marrow (n = 9), peripheral neuropathy (n = 6), cerebellar syndrome (n = 2), a pyramidal syndrome of the lower limbs (n = 4) and optic neuropathy (n = 1). Laboratory tests showed a mean hemoglobin concentration of 7.2 ± 1.5 g/dl, mean 104 ± 28 fl, macrocytic anemia in 10 patients. Biermer's disease was identified in 9 patients, 3 patients showed the syndrome of non dissociation of vitamin B12, a gastrectomy in 2 patients and no etiology was identified in 8 patients.

PMID:
23793871
[PubMed - indexed for MEDLINE]
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