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Int J Surg Case Rep. 2013;4(8):678-80. doi: 10.1016/j.ijscr.2013.04.036. Epub 2013 May 15.

Squamous cell carcinoma at an ileostomy site-Fifty-four years following colectomy for ulcerative colitis: A case report and literature review.

Author information

  • 1Mid Yorkshire Hospitals NHS Trust, Colorectal Unit, United Kingdom. Electronic address: farshid.e@doctors.org.uk.

Abstract

INTRODUCTION:

Carcinoma arising at an ileostomy site is an extremely rare occurrence. The rate of malignancy arising at an ileostomy site is reported as being 2-4 of every 1000 cases. The development of squamous cell carcinoma at the mucocutaneous junction of an ileostomy is extremely rare.

PRESENTATION OF CASE:

We present a case of a 76-year-old male who developed squamous cell carcinoma at an ileostomy site fifty-four years after total colectomy as management for ulcerative colitis.

DISCUSSION:

Our literature review has identified only four similar cases previously published in English literature. All cases of squamous cell carcinoma developing in ileostomy have occurred after a minimum of twenty-six years following ileostomy. This suggests that the etiology may be due to chronic factors.

CONCLUSION:

Patients with chronic stomal inflammation, bleeding or persistent induration and/or mass formation should be followed up closely and investigated for recurrence or development of a new malignancy. There should be a low threshold to obtain an early definitive tissue diagnosis by taking biopsies to prevent local or systemic invasion.

Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

KEYWORDS:

Crohn's; Ileostomy; Squamous cell carcinoma

PMID:
23792479
[PubMed]
PMCID:
PMC3710907
Free PMC Article
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