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Gastrointest Endosc. 2013 Nov;78(5):744-9. doi: 10.1016/j.gie.2013.05.004. Epub 2013 Jun 18.

Safety of capsule endoscopy in the octogenarian as compared with younger patients.

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  • 1Department of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, Florida, USA.

Abstract

BACKGROUND:

There has been an increased use of capsule endoscopy for the evaluation of small-intestine pathology in very elderly patients, yet the safety profile of this procedure has not been well-established.

OBJECTIVE:

To estimate the adverse event rate of capsule endoscopy in patients aged ≥80 years and to compare this rate with that of capsule endoscopy patients aged <80 years.

DESIGN:

Retrospective matched cohort study.

SETTING:

Single tertiary-care referral center.

PATIENTS:

All 195 patients aged ≥80 years who underwent capsule endoscopy between 2005 and 2011 were included, along with 585 capsule endoscopy patients aged <80 years who were matched by sex in a 1:3 fashion.

INTERVENTION:

All patients underwent capsule endoscopy and, in selected cases, double-balloon enteroscopy.

MAIN OUTCOME MEASUREMENTS:

Adverse event rate of capsule endoscopy, which was defined as capsule retention or aspiration.

RESULTS:

Adverse events occurred at a similar frequency in patients aged ≥80 years compared with those aged <80 years (1.03% vs 0.85%; P = 1.00), resulting in a difference of 0.2% (95% confidence interval, -1.8% to 2.1%). All adverse events were related to capsule retention, with no study patients experiencing aspiration.

LIMITATIONS:

This was a single-center, retrospective study.

CONCLUSION:

Adverse events resulting from capsule endoscopy occur at a similar rate in patients aged ≥80 years compared with those aged <80 years. Capsule endoscopy can be performed safely in the very elderly patient population.

Copyright © 2013 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

KEYWORDS:

CE; DBE; NSAID; OGIB; capsule endoscopy; double-balloon enteroscopy; nonsteroidal anti-inflammatory drug; obscure GI bleeding

PMID:
23790756
[PubMed - indexed for MEDLINE]
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