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Rinsho Shinkeigaku. 2013;53(6):439-45.

[Bilateral internal carotid artery occlusion and severe basilar artery stenosis in a patient with fibromuscular dysplasia: a case report].

[Article in Japanese]

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  • 1Department of Neurology, Social Insurance Chukyo Hospital.


Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory arterial disease of unknown etiology. We report a 26-year-old woman who presented with transient ischemic attack (TIA) due to bilateral internal carotid artery (ICA) occlusion and severe basilar artery stenosis, as FMD was diagnosed by a biopsy specimen of right ICA. Imaging investigations included magnetic resonance angiography and catheter angiogram without characteristic "string of beads" pattern, before reaching a definitive diagnosis by pathologist. Anti-platelet therapy and bypass surgery of superficial temporal artery-middle cerebral artery revealed no more clinical symptoms. This case of intra- and extra-cranial FMD gives a consideration of such rare disease in the differential diagnosis of TIA or stroke in healthy young patients. The literature of FMD is reviewed including pathological findings.

[PubMed - indexed for MEDLINE]
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