Gnathic osteosarcoma: a retrospective analysis over a 20 year period

Kathmandu Univ Med J (KUMJ). 2013 Jan-Mar;11(41):37-40. doi: 10.3126/kumj.v11i1.11024.

Abstract

Background: Osteosarcomas are very rare malignant mesenchymal neoplasms affecting jaw bones. Only few studies are reported about this lesion in this particular region.

Objective: We wanted to assess the demography and tumor behaviour and histopathological pattern, retrospectively in the available cases.

Methods: A retrospective analysis of hospital records for 20 years was carried out. Clinical features, radiographic findings, histopathological details and treatment aspect of each of the lesions was considered.

Results: Findings of this study revealed only 13 cases of gnathic osteosarcomas, usually occurring in middle age, with equal sex predilection and predominantly seen in maxilla. Histopathologically, most of them belonged to osteogenic variant.

Conclusion: Only few cases of gnathic osteosarcomas are reported in this region mainly in the young males. Interestingly many of them has history of dental extraction before the onset of disease.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Forecasting*
  • Humans
  • Incidence
  • Jaw Neoplasms / epidemiology
  • Jaw Neoplasms / pathology*
  • Male
  • Middle Aged
  • Nepal / epidemiology
  • Osteosarcoma / epidemiology
  • Osteosarcoma / pathology*
  • Prevalence
  • Retrospective Studies
  • Sex Distribution
  • Time Factors
  • Young Adult