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Cell Res. 2013 Aug;23(8):978-9. doi: 10.1038/cr.2013.78. Epub 2013 Jun 18.

Regeneration potential of adult cardiac myocytes.

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  • 1Department of Medicine, Center for Cardiovascular Biology, Institute for Stem Cell Research, University of Washington School of Medicine, Seattle, WA 98195, USA.

Abstract

Although adult cardiac myocytes (CMs) have very little proliferative potential, fetal CMs divide robustly. The mechanisms underlying the post-mitotic state of CMs are poorly understood; however, recently Mahmoud et al. identified a homeodomain transcription factor, Meis1, which controls postnatal CM cell cycle.

PMID:
23774267
[PubMed - indexed for MEDLINE]
PMCID:
PMC3731562
Free PMC Article
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