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Int J Trichology. 2012 Oct;4(4):265-70. doi: 10.4103/0974-7753.111223.

A study to evaluate the efficacy of various topical treatment modalities for alopecia areata.

Author information

  • 1Department of Dermatology, STD and Leprosy, Bharati Vidyapeeth Deemed University Medical College, Pune, India.

Abstract

CONTEXT:

Alopecia Areata (AA) is a common form of non-scarring hair disorder of unclear etiology. The disease may have serious psychological effect.

AIMS:

The objective is to assess the therapeutic effect and side effects of various topical modalities for the treatment of AA.

SETTINGS AND DESIGN:

Open, randomized, comparative study.

MATERIALS AND METHODS:

For this study, 30 patients were included of all age groups and both sexes having localized (<5 patches and <25% scalp involvement) alopecia, with no underlying disease or family history, and who had not received any treatment before. They were treated sequentially with 5 different combination regimes for 3 months. The response was assessed subjectively as well as objectively by the "Severity of Alopecia Tool Score".

STATISTICAL ANALYSIS:

Chi-square test.

RESULTS:

Out of the 5 modalities studied, the Intralesional and Topical Steroids were the most effective with no significant side effects.

CONCLUSIONS:

Among the various topical modalities used for the treatment of AA, the most effective are the Intralesional and Topical steroids with no significant side-effects.

KEYWORDS:

Alopecia areata; steroids; therapeutic modalities

PMID:
23766611
[PubMed]
PMCID:
PMC3681108
Free PMC Article
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