Objectives: To compare objective image quality indices in dual-energy CT angiography (DE-CTA) studies of the abdomen and lower extremity using conventional polyenergetic images (PEIs) and virtual monoenergetic images (MEIs) at different kiloelectron volt (keV) levels.
Methods: We retrospectively evaluated 68 dual-source DE-CTA studies. 50 patients (42 men, 71 ± 10 years) underwent abdominal DE-CTA. 18 patients (13 men, 67 ± 10 years) underwent lower extremity DE-CTA. MEIs from 40 to 120 keV were reconstructed. Signal intensity, noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were assessed in infrarenal aorta, superior mesenteric, external iliac, femoral, popliteal, and lower leg arteries. Comparisons between MEIs and PEIs were performed with Dunnett's test.
Results: 222 arteries were evaluated. In abdominal arteries 70 keV MEIs showed statistically equal signal intensity, noise and CNR levels (+13%; +31%, -14% on average; all p>0.05) compared to PEIs; SNR was equal or slightly impaired (-7% on average; p<0.001-1.00). In lower extremity arteries 60 keV MEIs resulted in significantly higher signal intensity and CNR (+54%; +54% on average; all p<0.05) compared to PEIs at equal noise levels (+18% on average; all p>0.05) and equal or higher SNR (+49% on average; p<0.01-0.35).
Conclusions: Low-keV MEIs lead to equal or higher signal intensity and CNR compared to PEIs. In lower extremity DE-CTA, additional reconstruction of low-keV MEIs at 60 keV might increase diagnostic confidence.
Keywords: CT angiography; Dual-energy CT; Dual-source CT; Image quality; Monoenergetic.
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