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Angew Chem Int Ed Engl. 2013 Jul 15;52(29):7477-81. doi: 10.1002/anie.201302455. Epub 2013 Jun 11.

Analysis of microarrays by MALDI-TOF MS.

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  • 1CICbiomaGUNE, Biofunctional Nanomaterials Unit, Paseo Miramon 182, 20009 San Sebastian, Spain.


Ligand libraries can be printed onto a sandwich composed of activated lipids embedded in a hydrophobic layer conjugated to an indium-tin oxide (ITO) surface. Arrays produced this way can be analyzed by fluorescence spectroscopy and mass spectrometry. Applications include the assignment of enzyme specificity, the profiling of glycoforms and the identification of lectins.

Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


lectins; mass spectrometry; microarrays; proteomics; transferases

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