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Macromol Biosci. 2013 Aug;13(8):1020-35. doi: 10.1002/mabi.201300013. Epub 2013 Jun 3.

An emerging functional natural silk biomaterial from the only domesticated non-mulberry silkworm Samia ricini.

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  • 1Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.

Abstract

Mulberry silk fibroin is a widely used biomaterial and recent work on non-mulberry silk fibroin also suggests it may have similar uses. We expect silk fibroin from the only domesticated non-mulberry eri silkworm, Samia ricini, to possess useful properties as a biomaterial. Eri silk gland fibroin is a heterodimeric protein of approximately 450‚ÄČkDa. Cytocompatibility evaluation with fibroblasts and osteoblast-like cells shows good cell attachment, viability and proliferation. The matrices, which have high thermal stability and good swellability, are also haemocompatible. Eri silk production is cost effective as no agronomic practices are required for their host plant cultivation. This fibroin provide new opportunities as an alternative natural functional biomaterial in various biomedical applications.

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

KEYWORDS:

Samia ricini; biomaterial; eri; fibroin; silk

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