[Fibrinogen-thrombin as bridge therapy in massive hemoptysis]

Biomedica. 2013 Jan-Mar;33(1):28-30. doi: 10.1590/S0120-41572013000100003.
[Article in Spanish]

Abstract

This article presents the case of a young woman with massive hemoptysis (1,000 mL in 6 hours) due to tuberculosis, which could not be controlled by insertion of a Fogarty catheter through a fiber-optic bronchoscope. Because of asphyxia and persistent bleeding risk we instilled fibrinogen-thrombin through a fiber-optic bronchoscope inserted catheter, achieving bleeding cessation and permitting the placing of a double-lumen oro-tracheal tube. Later on, the patient underwent lobectomy and anti-tuberculosis treatment. The fibrinogen-thrombin could be considered as a bridge, transitory measure for massive hemoptysis, while definitive treatment could be established.

Publication types

  • Case Reports
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use
  • Aprotinin / administration & dosage
  • Aprotinin / therapeutic use*
  • Balloon Occlusion
  • Bronchoscopy / methods
  • Catheters
  • Cholangiopancreatography, Endoscopic Retrograde / instrumentation
  • Combined Modality Therapy
  • Drug Combinations
  • Emergencies
  • Factor XIII / administration & dosage
  • Factor XIII / therapeutic use*
  • Female
  • Fiber Optic Technology
  • Fibrin Tissue Adhesive / administration & dosage
  • Fibrin Tissue Adhesive / therapeutic use*
  • Fibrinogen / administration & dosage
  • Fibrinogen / therapeutic use*
  • Hemoptysis / etiology
  • Hemoptysis / surgery
  • Hemoptysis / therapy*
  • Hemostatic Techniques* / instrumentation
  • Humans
  • Intubation, Intratracheal / instrumentation
  • Pneumonectomy
  • Thrombin / administration & dosage
  • Thrombin / therapeutic use*
  • Tuberculosis, Pulmonary / complications
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / surgery

Substances

  • Antitubercular Agents
  • Drug Combinations
  • Fibrin Tissue Adhesive
  • beriplast P combi set
  • Fibrinogen
  • Factor XIII
  • Aprotinin
  • Thrombin