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J Clin Virol. 2013 Aug;57(4):370-3. doi: 10.1016/j.jcv.2013.04.022. Epub 2013 May 23.

Human T-lymphotropic virus type 1 infective dermatitis in central Australia.

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  • 1Northern Territory Rural Clinical School, Flinders University, 0870 Alice Springs, Northern Territory, Australia. lloyd.einsiedel@nt.gov.au

Abstract

The Human T-Lymphotropic Virus type 1 (HTLV-1) is a single-stranded RNA retrovirus that preferentially infects CD4+ T cells. The spectrum of diseases that are associated with the most frequent genotype, the HTLV-1 cosmopolitan subtype A, has been well described. In contrast, very few cases of HTLV-1 related diseases have been reported for the HTLV-1 subtype C variant, which is endemic to Australia and the nearby islands of Melanesia. Here we describe the first case of infective dermatitis associated with the HTLV-1 Australo-Melanesian subtype C. This was complicated by repeated episodes of invasive infection with Staphylococcus aureus and illustrates the life-threatening nature of infective dermatitis among HTLV-1 carriers who live in conditions of social disadvantage.

Copyright © 2013 Elsevier B.V. All rights reserved.

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