A case of malignant lymphoma with a variety of ophthalmological findings was reported. The patient was a 65-year-old man with malignant lymphoma in retro-peritoneum (stage IV). Uveitis with hypopyon and secondary glaucoma appeared in his right eye, optic neuritis in his left eye. We compared clinical observations with histopathological findings and found that glaucoma was due to direct obstruction in the trabecular space by tumor cells and optic neuritis was due to the tumor cell infiltration into optic nerve.