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Pediatr Int. 2013 Apr;55(2):e23-4. doi: 10.1111/j.1442-200X.2012.03730.x.

Subcutaneous fat necrosis after selective head cooling in an infant.

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  • 1Department of Neonatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.


Hypoxic-ischemic encephalopathy in neonates causes irreversible damage to tissue and organs and results in multiple organ failure and poor outcome. Therapeutic hypothermia is the most effective therapy in neonates with hypoxic-ischemic encephalopathy. We report here a case of subcutaneous fat necrosis (SCFN) after therapeutic hypothermia by selective head cooling. Selective head cooling was provided for 72 h after birth. SCFN developed on the patient's cheeks and back at the age of 21 days. Thus, SCFN may be caused by selective head cooling, similarly to whole-body cooling.

© 2013 The Authors. Pediatrics International © 2013 Japan Pediatric Society.

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