Format

Send to:

Choose Destination
See comment in PubMed Commons below
Analyst. 2013 Jun 21;138(12):3502-11. doi: 10.1039/c3an36276k. Epub 2013 May 13.

An automated method for baseline correction, peak finding and peak grouping in chromatographic data.

Author information

  • 1Dept. Food Science, University of Copenhagen, Denmark. rb@life.ku.dk

Abstract

An automated method (FastChrom) for baseline correction, peak detection and assignment (grouping) of similar peaks across samples has been developed. The method has been tested both on artificial data and a dataset obtained from gas chromatograph analysis of wine samples. As part of the automated approach, a new method for baseline estimation has been developed and compared with other methods. FastChrom has been shown to perform at least as well as conventional software. However, compared to other approaches, FastChrom finds more peaks in the chromatograms and not only those with retention times defined by the user. FastChrom is fast and easy to use and offers the possibility of applying a retention time index which facilitates the identification of peaks and the comparison between experiments.

PMID:
23665697
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry
    Loading ...
    Write to the Help Desk