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J Asian Nat Prod Res. 2013;15(6):619-23. doi: 10.1080/10286020.2013.791286. Epub 2013 May 10.

Two new neuroprotective phenolic compounds from Gastrodia elata.

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  • 1School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.

Abstract

Two new phenolic compounds 4-(4'-hydroxybenzyl) phenyl glucoside (gastrodin B, 1) and 1'-hydroxymethyl-phenyl 4-hydroxy-3-(4″-hydroxybenzyl) benzyl ether (gastrol B, 2) were isolated from the rhizomes of Gastrodia elata. Their structures were elucidated on the basis of spectroscopic data and chemical reaction. All compounds exhibited potent neuroprotective activity against H2O2-induced PC12 cell damage.

PMID:
23659598
[PubMed - indexed for MEDLINE]
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