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Cir Pediatr. 2012 Oct;25(4):187-92.

[Increase of newborns with anorectal malformation in 2011. Is it just by chance?].

[Article in Spanish]

Author information

  • 1Hospital Materno-lnfantil Infanta Cristina, SES, UEX, Grupo de Investigación en Pediatría PAIDOS (CTS 019), Badajoz. cmorenohurtado@yahoo.com

Abstract

OBJECTIVE:

In 2011 we have diagnosed 9 anorectal malformations (MAR). This means 13.3 cases/10.000 NB versusu the estimated incidence of 2 cases/10.000 NB. This accumulation of defects can not be due to chance, so we have decided to focus on its research.

MATERIAL AND METHODS:

The study included all the patients with anorrectal malformations born in 2011. In all of them we analyzed: geographic area, age and health status of parents, pregnancy, exposure to teratogens, especially lorazepam intake, sex, gestational age, weight at birth, exploration of the abdomen and perineum, birth defects associated, imaging studies performed, treatment and current situation.

RESULTS:

All patients came from our province, and maternal age is under 20 years in 2 patientes and older than 30 in 7; male-dominated (8/1); low forms in 4 of 9 patients. 100% of newborns have some type of associated malformation, in genitals, urinary system or costovertebral. Clinical assessment and imaging study provided the right diagnosis in all the cases. It must be noted the absence of difficulties in the surgery treatment and a favorable outcome in all children.

CONCLUSIONS:

To this accumulation of cases with anorrectal malformation cases it is added a male predominanced, and a high incidence of associatedmalformations and high defects. We have not found an epidemiological explanation for this concentration of patients with anorrectal malformations. This forces us to continue our investigation if detected for some reason, currently not known.

PMID:
23659019
[PubMed - indexed for MEDLINE]
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