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Chem Pharm Bull (Tokyo). 2013;61(5):546-50.

A study of the various factors that affect the properties of molecularly imprinted polymers.

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  • 1Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0972, Japan.

Abstract

We evaluated the adsorbability and selectivity of (S)-valine anilide imprinted molecularly imprinted polymer (MIP) using a batch procedure that is both independent and precise. This study revealed important information about the relationship between the performance of MIPs and experimental factors such as the components of MIP synthesis and a reaction solvent. Herein, we also describe the problems associated with the preparation of a "non-imprinted polymer," which is often used to evaluate the effect of a template molecule, and we propose a new type of reference polymer, "blank polymer."

PMID:
23649197
[PubMed - indexed for MEDLINE]
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