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Ultrasound Med Biol. 2013 Jul;39(7):1223-32. doi: 10.1016/j.ultrasmedbio.2013.02.002. Epub 2013 Apr 30.

Assessment of the fundamental flexural guided wave in cortical bone by an ultrasonic axial-transmission array transducer.

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  • 1Department of Physics, University of Jyväskylä, Jyväskylä, Finland. warma@iki.fi

Abstract

The fundamental flexural guided wave (FFGW), as modeled, for example, by the A0 Lamb mode, is a clinically useful indicator of cortical bone thickness. In the work described in this article, we tested so-called multiridge-based analysis, based on the crazy climber algorithm and short-time Fourier transform, for assessment of the FFGW component recorded by a clinical array transducer featuring a limited number of elements. Methods included numerical finite-element simulations and experiments in bone phantoms and human radius specimens (n = 41). The proposed approach enabled extraction of the FFGW component and determination of its group velocity. This group velocity was in good agreement with theoretical predictions and possessed reasonable sensitivity to cortical width (r(2) = 0.51, p < 0.001) in the in vitro experiments. It is expected that the proposed approach enables related clinical application. Further work is still needed to analyze in more detail the challenges related to the impact of the overlying soft tissue.

Copyright © 2013 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

PMID:
23643059
[PubMed - indexed for MEDLINE]
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