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Fertil Steril. 2013 Jul;100(1):39-42. doi: 10.1016/j.fertnstert.2013.03.013. Epub 2013 Apr 30.

Hyperandrogenism during puberty in the development of polycystic ovary syndrome.

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  • 1Department of Obstetrics and Gynecology, University of Texas Medical School, Houston, Texas 77030, USA.


The hormonal events of puberty, from adrenarche to menarche and beyond, include the secretion of androgens as well as estrogen and P. This normal pubertal process is briefly reviewed and a physiologic role for pubertal androgens proposed. It is further suggested that the hyperandrogenic state we call polycystic ovary syndrome is a maladaptation of the advantageous role of normal pubertal androgens.

Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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