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Arch Pathol Lab Med. 1990 Jul;114(7):727-8.

Fluoxetine and the bleeding time.

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  • 1Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville 22908.

Abstract

Fluoxetine (Prozac) is a nontricyclic serotonin (5-hydroxytryptamine) reuptake inhibitor commonly prescribed for the treatment of depression. Fluoxetine also blocks 5-hydroxytryptamine reuptake in platelets and could potentially lead to clinically significant platelet dysfunction. We describe a patient who developed petechiae and prolongation of the bleeding time while receiving fluoxetine therapy.

PMID:
2363631
[PubMed - indexed for MEDLINE]
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