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Am J Clin Nutr. 2013 Jun;97(6):1375-86. doi: 10.3945/ajcn.112.038489. Epub 2013 May 1.

Diet spanning infancy and toddlerhood is associated with child blood pressure at age 7.5 y.

Author information

  • 1Department of Medicine, The University of Melbourne, Melbourne, Australia. laimab@unimelb.edu.au

Abstract

BACKGROUND:

Diet in the first 2 y of life may be a pivotal period regarding effects on future blood pressure (BP). However, data on early-life diet and BP in childhood are sparse.

OBJECTIVE:

We prospectively assessed associations between types of diet spanning infancy and toddlerhood (ie, transition diets across the complementary feeding period) and BP at age 7.5 y.

DESIGN:

In a birth cohort study (Avon Longitudinal Study of Parents and Children; United Kingdom), a total of 1229 children had complete dietary intake data at 6, 15, and 24 mo; BP data at 7.5 y of age; and all 18 covariables.

RESULTS:

Of the 2 transition diets that were extracted by using principal components analysis, the less-healthy diet was associated with an increase in systolic BP of 0.62 mm Hg (95% CI: 0.00, 1.24 mm Hg) and an increase in diastolic BP of 0.55 mm Hg (95% CI: 0.10, 1.00 mm Hg) for every one-unit (SD) increase in the less-healthy-diet score after adjustment for 15 potential confounders, including maternal characteristics and sociodemographic factors, birth variables, and breastfeeding duration. In contrast with systolic BP, the positive association between the less-healthy transition-diet score and diastolic BP persisted after additional adjustment for child body-size factors [height, body mass index (BMI), and waist circumference] at 7.5 y.

CONCLUSIONS:

A less-healthy transition diet by age 2 y was associated with higher BP at 7.5 y. The BMI-related reduction in effect size reinforces the importance of BMI on the diet-BP relation.

PMID:
23636239
[PubMed - indexed for MEDLINE]
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