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Wideochir Inne Tech Maloinwazyjne. 2013 Mar;8(1):13-21. doi: 10.5114/wiitm.2011.30828. Epub 2012 Sep 29.

Metabolic changes one year after laparoscopic adjustable gastric banding operation in morbidly obese subjects.

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  • 1Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania ; Vilnius University Faculty of Medicine, Vilnius, Lithuania.

Abstract

INTRODUCTION:

Laparoscopic adjustable gastric banding (LAGB) is effective for weight reduction in severely obese patients. However, the data about its effect on metabolic syndrome (MS) are limited.

AIM:

To assess weight loss and changes of metabolic parameters 1 year after LAGB in a prospective, nonrandomized single center cohort study in morbidly obese subjects.

MATERIAL AND METHODS:

Physical examination, body weight (BW) parameters and metabolic profile were assessed at baseline and 1 year after LAGB in morbidly obese subjects. The incidence of MS was evaluated according to National Cholesterol Education Program Adult Treatment Panel III criteria.

RESULTS:

One year after the operation data from 90 patients out of 103 were available. Mean excess weight (EW) loss of 33.1% was associated with a significant improvement in all metabolic parameters: decrease of hypertension by 15.8%, hypertriglyceridemia by 42.6%, and hyperglycemia by 46.3%; and increase in high density lipoprotein cholesterol by 48.3%. This resulted in the resolution of MS in 44.2% of subjects. The significant change in the distribution of MS components was observed with the highest frequency of 4 components before and 2 components after surgery. Patients with MS at baseline lost 29.9% of EW compared to 44.3% in those without MS (p = 0.009).

CONCLUSIONS:

The LAGB resulted in effective reduction of BW parameters in morbidly obese subjects 1 year after the operation. Along with the weight loss, resolution of MS and a significant shift towards decrease in the number of MS components was observed. Patients with MS were more resistant to the weight loss.

KEYWORDS:

bariatric surgery; laparoscopic adjustable gastric banding; metabolic syndrome; obesity

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