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Chem Commun (Camb). 2013 May 28;49(43):4971-3. doi: 10.1039/c3cc42179a.

Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification.

Author information

  • 1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. minlay@stanford.edu

Abstract

We report the design of a water-soluble, quaternized tamoxifen photoprobe and demonstrate its application in light-controlled induction of green fluorescent protein expression via a Cre-ER recombinase system.

PMID:
23612712
[PubMed - indexed for MEDLINE]
PMCID:
PMC3926663
Free PMC Article

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