Hepatitis E virus serological testing in kidney transplant recipients with elevated liver enzymes in 2007-2011 in southeastern France

Valérie Moal; Anne Motte; Mamadou Kaba; René Gerolami; Yvon Berland; Philippe Colson

doi:10.1016/j.diagmicrobio.2013.02.017

Hepatitis E virus serological testing in kidney transplant recipients with elevated liver enzymes in 2007-2011 in southeastern France

Diagn Microbiol Infect Dis. 2013 May;76(1):116-8. doi: 10.1016/j.diagmicrobio.2013.02.017.

Authors

Valérie Moal¹, Anne Motte, Mamadou Kaba, René Gerolami, Yvon Berland, Philippe Colson

Affiliation

¹ Assistance Publique - Hôpitaux de Marseille, Hôpital Conception, Centre de Néphrologie et Transplantation rénale, 13385, Marseille, France.

PMID: 23608351
DOI: 10.1016/j.diagmicrobio.2013.02.017

Abstract

Hepatitis E virus (HEV) is an emerging cause of acute and chronic hepatitis in Europe, particularly in solid organ transplant recipients. Anti-HEV IgG/IgM testing in kidney transplant recipients with liver biological disturbances indicated high HEV exposure in our geographical area and led to diagnose HEV infection in 6% of cases.

MeSH terms

Antibodies, Viral / blood
France / epidemiology
Hepatitis E / diagnosis*
Hepatitis E / epidemiology
Hepatitis E / virology
Hepatitis E virus / isolation & purification*
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Kidney Transplantation / adverse effects*
Liver / enzymology
Liver Diseases / physiopathology
RNA, Viral / isolation & purification
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Serology

Substances

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M
RNA, Viral