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Oncol Lett. 2013 Apr;5(4):1311-1314. Epub 2013 Jan 22.

Composite tumor of metanephric adenoma and Wilms' tumor of the kidney: A case report and review of the literature.

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  • 1Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030;


Metanephric adenoma (MA) and Wilms' tumor (WT) are two distinct types of renal tumors. Composite MA and WT of the kidney are extremely rare. Here, a rare case of composite MA and WT of the kidney in a 36-year-old male is described. MA and WT each have their own histopathological features, respectively, and they focally share morphological similarities, which can be a diagnostic challenge. Immunohistochemistry is useful in the differential diagnosis of MA and WT. The histopathological features and differential diagnosis of the composite tumor are emphasized here to promote a better and broader understanding of this less understood subject.


Wilms’ tumor; composite tumor; differential diagnosis; metanephric adenoma

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