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Biomed Opt Express. 2013 Apr 1;4(4):619-34. doi: 10.1364/BOE.4.000619. Epub 2013 Mar 28.

Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT.

Author information

  • 1Lehrstuhl für BioMolekulare Optik, Fakultät für Physik, Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538 Munich, Germany.

Abstract

Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ultra high speed in-vivo imaging. JA-OCT is compared to other angle-resolved techniques, and the relation between joint aperture imaging, adaptive optics, coherent and incoherent compounding is discussed. We present angle-resolved imaging of the human retina at an axial scan rate of 1.68 MHz, and demonstrate the benefits of JA-OCT: Speckle reduction, signal increase and suppression of specular and parasitic reflections. Moreover, in the future JA-OCT may allow for the reconstruction of the full Doppler vector and tissue discrimination by analysis of the angular scattering dependence.

KEYWORDS:

(030.6140) Speckle; (120.3890) Medical optics instrumentation; (170.3880) Medical and biological imaging; (170.4500) Optical coherence tomography

PMID:
23577296
[PubMed]
PMCID:
PMC3617723
Free PMC Article

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