Mutational analysis of GNAQ and GNA11 to aid therapy management of a choroidal melanoma metastatic to the contralateral orbit

JAMA Ophthalmol. 2013 Jun;131(6):812-4. doi: 10.1001/jamaophthalmol.2013.1921.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Choroid Neoplasms / genetics*
  • Choroid Neoplasms / pathology
  • Choroid Neoplasms / therapy
  • DNA Mutational Analysis*
  • GTP-Binding Protein alpha Subunits / genetics*
  • GTP-Binding Protein alpha Subunits, Gq-G11
  • Genetic Predisposition to Disease
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Melanoma / genetics*
  • Melanoma / secondary
  • Melanoma / therapy
  • Middle Aged
  • Mutation*
  • Orbital Neoplasms / genetics*
  • Orbital Neoplasms / secondary
  • Orbital Neoplasms / therapy
  • Phenotype
  • Precision Medicine
  • Predictive Value of Tests

Substances

  • GNA11 protein, human
  • GNAQ protein, human
  • GTP-Binding Protein alpha Subunits
  • GTP-Binding Protein alpha Subunits, Gq-G11