PKCλ: a new player in LTP coming to the rescue of PKCζ's faltering role in LTP?

EMBO J. 2013 May 15;32(10):1348-9. doi: 10.1038/emboj.2013.81. Epub 2013 Apr 5.

Abstract

EMBO J (2013) 32 10, 1365–1380. doi:; DOI: 10.1038/emboj.2013.60

Long-term potentiation (LTP) of synaptic transmission has received widespread attention because it is thought to form the physiological basis of learning and memory. A new paper in The EMBO Journal identifies the atypical PKC family member PKCλ as an important contributor to the strengthening of the postsynaptic response in LTP.

Publication types

  • Comment

MeSH terms

  • Animals
  • Isoenzymes / metabolism*
  • Long-Term Potentiation / physiology*
  • Male
  • Protein Kinase C / metabolism*

Substances

  • Isoenzymes
  • Protein Kinase C
  • protein kinase C lambda